Death on Two Legs: Analyzing the initial 20 weeks of the 1636 London plague outbreak using time-to-event analysis. During the seventeenth century, England experienced multiple plague outbreaks. Although milder than the 1603 and 1624 plague crisis, London’s outbreak of 1636 claimed the lives of roughly 10,400 individuals, approximately 7.5% of the population in London and its liberties.1 In this blog post, I delve into the first stages of the 1636 outbreak, by scrutinizing the propagation of the plague through London’s city subdivisions, with the aid of time-to-event analysis.